Eleven cases of adult malignant rhabdoid tumor of kidney:a clinical analysis
HUANG Ming-wen
LIU Li-wei
WANG Jin-zhu
CAO Li-rui
BAI Tie-nan
Abstract：Objective To observe the diagnosis , treatment and prognosis of adult malignant rhab doid tumor of the kidney .Methods The clinical data from 11 patients with adult malignant rhabdoid tumor of the kidney were retrospective-ly analyzed.Results The main clinical manifestations of 11 patients:waist pain was found in 4 cases, gross hematuria in 2 cases, weight loss and fatigue in 2 cases.B-ultrasonic examination showed all had renal lesions , computed tomography ( CT) revealed mixed density irregularities mixed with renal tumor shadow and liquefaction necrosis within the tumor , and enhanced scan showed that all had heterogeneous enhancement changing .Eleven cases underwent radical nephrectomy com-bined with postoperative immune therapy .According to the NWTS3 staging system, 4 cases had stageⅠtumor, 5 cases had stage Ⅱtumor and 2 cases had stage Ⅲtumor.Four cases died of multiple organ metastasis within 1 year after operation, 3 cases died of myocardial infarction , cerebral hemorrhage or renal failure , and 3 cases were follwed up for 7 to 26 months with disease-free survival .Conclusions The clinical manifestations of adult malignant rhabdoid tumor of the kidney have no specificity , the final diagnosis depends on pathological examination , and radical nephrectomy and retroperitoneal lymph node dissection should be done as early as possible .Immune therapy promptly after operation for stageⅠandⅡtumors re-sponds well for the prognosis , but poor efficacy for stage Ⅲand Ⅳtumors.
Keywords：kidney neoplasmsmalignant rhab doid tumorradical nephrectomy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 37-39 )