Logistic regression analysis on clinical features and related risk factors of primary gout in the northeastern area of China
LI Ling-qin
QING Yu-feng
ZHOU Chang
ZHOU Jing-guo
Abstract：Objective To explore the clinical features and related risk factors of primary gout in the northeastern area of China .Methods A clinical investigation and related laboratory indicator detections of primary gout were made on 583 cases of patients with primary gout and 459 healthy persons by a unified questionnaire .Then, logistic regression analysis was applied in analyzing related risk factors .Results (1) Only a joint was involved in the first attack of 94.9% of pa-tients, while the first metatarsophalangeal joint accounted for 68.6%.(2) 37.6%of patients didn't have predisposing fac-tors, 62.4%of patients had predisposing factors , during which 88.2%of 364 patients was related with beer, sea food and other dietary factors.(3) The rates of patients complicated with tophus , hypertension and hyperlipidemia were 12.2%, 35.7%and 66.9%.(4) Tophus occurred in the 3-8 years after the gout, when we compared with patients without tophus , the course of disease was longer , and the level of serum uric acid ( SUA) was significantly higher than that of patients with tophus (all P<0.01).(5) Logistic regression analysis indicated the occurrence of primary gout was related to the follow-ing factors:hyperuricemia, drinking, BMI, hypertriglyceridemia, eating habits, hypertension and smoking (P<0.01 or P<0.05).Conclusion Primary gout is affected by many factors; hyperuricemia, drinking, BMI, high TG, high purine diet, hypertension and smoking may increase the onset risk .
Keywords：goutprimaryclinical characteristicsrisk factorslogistic regression analysis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 13-15 )