Preventive effect of Guanxin Danshen dripping pills on restenosis after coronary stent implantation
ZHANG Hong-xing
CHAI Xue-yun
Abstract:Objective To observe the clinical curative effect and mechanism of Guanxin Danshen dropping pills on the restenosis after coronary stent implantation .Methods Sixty patients who underwent coronary stent implantation were randomly divided into the experimental group and control group , 30 cases in each group .After the operation , the control group was treated with conventional Western medicine , and the experimental group was treated with conventional Western medicine combined with Guanxin Danshen dropping pills .The restenosis rate, incidence of cardiovascular events ,changes in the clinical symptom of the two groups in 6 months after the coronary stent implantation were observed , the postoperative ventricular function and the levels of IL-18 and high-sensitivity C-reactive protein ( Hs-CRP) were compared .Results Six months after the coronary stent implantation , TCM symptoms curative effect of the experimental group was superior than the control group (P<0.05) and the incidence of major adverse cardiovascular events of the experimental group was signifi -cantly lower than that of the control group (P<0.05).There were significant differences in ventricular wall motion index , left ventricular ejection fraction and IL-18 and Hs-CRP levels between the two groups (all P<0.05).Conclusion Guanx-in Danshen dropping pills have significant effect in reducing the rate of restenosis after coronary stent implantation .
Keywords:coronary diseaseGuanxin Danshen dropping pillscoronary stent implantationrestenosis
Publication Date:2014-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 23-25 )
