Expression of TMEM135 in a variety of tissues
XUE Bing-ying
ZHANG Peng
LI Xiao-long
QU Cong
LONG Jia-min
ZHOU Su-fang
Abstract：Objective To study the expression of TMEM 135 mRNA and protein in a variety of normal and tumor tis-sues.Methods We used in situ RT-PCR and immunohistochemistry to detect the expression of TMEM 135 mRNA and protein in 118 cases of normal tissues , 18 cases of benign and 55 cases of malignant tissues .Results TMEM135 mRNA and protein expressed widely in the human tissues .TMEM135 mRNA mainly distributed in the nuclear membrane and the protein was mainly in the cytoplasm which was mostly grainy distributed .There was significant difference in the expression of TMEM135 protein between normal and cancer tissues .Conclusion TMEM135 might be a protein which is associated with the tumor .
Keywords：tumorTMEM135in situ RT-PCRimmunohistochemistry
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 9-11 )