Predictive value of preoperative Fib-4 index on postoperative recurrence of hepatocellular carcinoma after hepatectomy
ZHU Geng-long
YANG Lu-kun
LIN Zhi-dong
HONG Xiao-peng
CHEN Dong
ZHANG Bai-meng
Abstract：Objective To investigate the postoperative recurrence predictive value of preoperative Fib -4 index on hep-atocellular carcinoma patients .Methods Clinical data of 67 cases of hepatocellular carcinoma underwent hepatectomy in the 5th Hospital Affiliated to Sun Yat-sen University were analyzed retrospectively .According to the preoperative Fib-4 in-dex, these patients were divided into 2 groups, one was Fib-4 index<3.25, the other was Fib-4 index≥3.25.These pa-tients were follow-up visited by using outpatient service and telephone till 2013 September .Cox ratio risk pattern analysis was used for the recurrent correlative factors .Results Univariate analysis showed that preoperative AFP≥400 ug/L, the maximum diameter of the tumor >5cm, the number of tumor>3, Fib-4 index≥3.25, vascular invasion, positive resection margin and portal vein tumor thrombus were all risk factors of poor disease -free survival (all P<0.05).Cox regression a-nalysis revealed that Fib-4 index≥3.25, the number of tumor >3 and portal vein tumor thrombus were independent predic-tors of poor disease-free survival after hepatectomy for hepatocellular carcinoma (all P<0.05).Conclusion Preoperative Fib-4 index≥3.25 is an independent risk factor for predicting the postoperative recurrence of patients with hepatocellular carcinoma.
Keywords：hepatocellular carcinomaFib-4 indexpostoperative recurrence
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 4-6 )