The significants and changes of urine microglobin and transferrin in essential hypentensive patients
Abstract：To study the changes of microglobin and transferrin in essentialhypertensive patients and the effect of amlodipine therapy，the concentration of urinary β2-MG，α1-MG and transferrin in 60 essential hypertensive patients and 30 normal persons were measured before and after amlodipine treatment.The result showed that the concentration of urinary β2-MG，α1-MG and transferrin in mild and moderate EH group were significantly higher than that in the control group（P＜0.01）and were significantly lower after amlodipine treatment than that before treatment （P＜0.01，P＜0.001）.This suggestS that cletation of urinary β2-MG，α1-MG and transferrin may identify hypertensive kidney injury earlier.Amlodipine can protect and prevent the occurence and Progression of kidney injury besides its antihypertensive effect.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 8-9 )