Relationship between insulin resistance and atherothromb-otic cerebral infarction and contents of plasma lipid
Zhang Guifang
ZHAO Renliang
Abstract：To investigate the relationship between insulin resistance （IR）and atherothrombotic cerebral infarction（ATCI）and contents of plasma lipid.Fasting plasma glucose（FPG），fasting insulin（FINS）and lipids were determined，and insulin sensitivity index（ISI）were calculated in 56 cases of patients with ATCI，only nondiabetic subjects with normotention were chosen to participate in this study.The correlations between ISI and contents of plasma lipid were also analysed.Results showed that FINS level was significantly elevated （P＜0.001）and ISI was markedly decreased（P＜0.001）in patients compared with the control（n＝30）.Moreover，ISI correlated positively with HDL-c （r＝0.42，P＜0.01）and apoA1（r＝0.34，P＜0.05），while correlated negatively with TG（r＝－0.39，P＜0.01），LDL-c（r＝－0.28，P＜0.05）.The results suggest that IR in association with dyslipidemia may play a crucial role in the development of patients with ATCI.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 5-6 )