Changes of TNFα and interleukins of patients with myeloproliferative disorders
Abstract：Serum TNFα and interleukins were measured in 26 patients withmyeloproliferative disorders（MPD）by ELISA or RIA method.Elavated IL-2 and β2-MG levels were found in MPD patients，TNFα was slightly increased.There were no difference of IL-6 and sIL-6R levels between MPD and normal controls.In progressive disease and particularly when transformation to acute leukemia occurred，high levels of IL-2，sIL-2R and β2-MG were found in all patients.These results suggest that IL-2，sIL-2R and β2-MG could be as a potential prognostic usefulness in the individual patients.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 5-6 )