change of the thromboxane and prostacyclin level before and after percutaneous balloon mitral valvuloplasty
Abstract：Thromobixane (TXB2)and prostacyclin (6-K-PGF1a)were measured in51 patients with percutaneous balloon mitral valvuloplasty(PBMV)before and after the procedure respectively,and 30 volunteers as normal control group. The data was carried out for relationship analysis with area of mitral valve(MVA),left artral diameter(LAD),average transmural pressure of mitral valve(MVPG),cardial index(CI),mean left artrial pressure (MLAP) and right ventricular systolic pressure (RVSP). The result showed TXB2 was higher and 6-K-PGF1a was lower than the control before PBMV(P＜0.05) ,TXB2 decreased and 6-K-PGF1a increased after PBMV (P＜0.01). TXB2 and MVA have a negtively association(r= -0.48,P＜0.05). These suggest that changes of TXB2 and 6-K-PGF1a levels after PBMV have a significant association with MVA and MLAP.
Keywords：Mitral valve stenosis Percutaneous balloon miteal valvuloplastyThronboxane Prostacyclin
Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 7-8 )