Changcs and clinical value of plasrma t-PA and PAI of patients with subarachnoid hemorrahage
Abstract：The plasma tissue-type plasminogen activator（t-PA），plasminogenactivator inhibitor-1（PAI-1）in 28 patients with subarachnoid hemorrhage（SAH） were observed and compared with 30 healthy controls.Result showed that the fibrinolytic activity of patients with SAH on day 1～14 were significantly higher than that of normal controls.Plasma PAI-1 activity of patients with cerebral vascular spasma（CVS） were higher than those without CVS on day 7，14.The more was the amount of bleeding，the more were the levels of t-PA and PAI-1.It suggests that the activity of plasma t-PA and PAI-1 are dynamic changing.Both of them may involve in the development and prognosis of SAH.Determination of t-PA and PAI-1 are efficient items for early finding，diagnosis of CVS and amount of bleeding in patients with SAH.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 6-8 )