Clinical Study on Rumo Huangji Formula(乳没黄及方)Chinese Herbal Fomentation Combined with TDP Irradiation in Treating Patients with Postoperative Perianal Edema of Mixed Hemorrhoids with Damp-heat and Blood Stasis

XU Ying; FAN Yibin; WEN Yuan

doi:10.16295/j.cnki.0257-358x.2026.01.008

Abstract：Objective:To analyze the clinical efficacy of Rumo Huangji Formula(乳没黄及方)Chinese herbal fomentation combined with specific electromag-netic spectrum(TDP)irradiation in the treatment of postoperative perianal edema of mixed hemorrhoids with damp-heat and blood stasis,and its effect on the anal function and pro-angiogenic factors of patients.Methods:A total of 140 patients with mixed hemorrhoids with damp-heat and blood stasis who were treated in our Hospital from June 2023 to June 2024 were prospectively selected and divided into a control group and an observation group by using the random number table method,with 70 cases in each group.The control group was treated with TDP irradiation combined with warm water sitz bath after the operation,while the observation group was treated with Rumo Huangji Formula Chinese herbal fomentation combined with TDP irradiation after the operation.The clinical efficacy,traditional Chinese medicine syndrome score,anal function and pro-angiogenic factors,inflammatory factor levels,and adverse reactions of the two groups were compared.Results:After treatment,the total effective rate of the observation group was higher than that of the control group(P＜0.05).After treatment,the TCM syndrome scores,the longest contraction time of the anal canal(ALCT),tumor necrosis factor-α(TNF-α),interleukin-1 β(IL-1β),interleukin-6(IL-6),and C-reactive protein(CRP)levels of the two groups of patients were all lower than those before treatment.The levels of anal systolic blood pressure(ASP),anal diastolic blood pressure(A DP),anal resting blood pressure(ARP),vascular endothelial growth factor(VEGF),fibroblast growth factor-1(FGF-1),fibronectin(FN),and transforming growth factor-β1(TGF-β1)were all higher than those before treatment(P＜0.05).Moreover,the levels of TCM syndrome score,ALCT,TNF-α,IL-1β,IL-6 and CRP in the observation group were lower than those in the control group,while the levels of ASP,ADP,ARP,VEGF,FGF-1,FN and TGF-β1 in the observation group were higher than those in the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions:Rumo Huangji Formula Chinese herbal fomentation combined with TDP irradiation can improve the levels of angiogenic factors and inflammatory factors,alleviate clinical symptoms such as anal edge edema,enhance the anal function of patients,and promote their recovery in the treatment of patients with perianal edema of mixed hemorrhoids with damp-heat and blood stasis.