Clinical Study on Guizhi Fuling Decoction(桂枝茯苓汤)Retention Enema Combined with Biofeedback Electrical Stimulation in Treatment of Pelvic Congestion Syndrome

WU Yan; SONG Jingyi; ZHONG Yuqing; CHEN Xiaohui; FANG Xin; LIU Jihong

doi:10.16295/j.cnki.0257-358x.2025.08.013

Abstract：Objective:To explore the effect of Guizhi Fuling Decoction(桂枝茯苓汤)retention enema combined with biofeedback electrical stimulation on pain and pelvic vein in patients with pelvic congestion syndrome(PCS).Methods:One hundred patients with PCS were divided into a control group and an observation group by the random number table method,with 50 cases in each group.Patients in the control group received biofeedback electrical stimulation treatment 3 to 7 days after the end of menstruation,while the observation group was treated with Guizhi Fuling Decoction retention enema on the basis of the treatment of the control group.Patients in both groups were treated for 3 menstrual cycles.After treatment,the clinical efficacy,Visual Analogue Scale(VAS)score,pelvic vein inner diameter,pelvic vein blood flow velocity,serum prostaglandin(PGE2,PGF2α)levels,and hemorheological indicators[plasma viscosity,high whole blood viscosity,fibrinogen(FIB)]of the two groups were compared.Results:After treatment,the total effective rate was 94.00％in the observation group and 76.00％in the control group.The comparison of therapeutic effects between the two groups showed a statistically significant difference(P＜0.05).After treatment,the VAS scores of the patients in both groups decreased,and those of the observation group were lower than those of the control group(P＜0.05).After treatment,the inner diameters of pelvic veins in both groups decreased,and the venous blood flow velocities increased.Moreover,the inner diameter of pelvic veins in the observation group was lower than that in the control group,and the venous blood flow velocity in the observation group was higher than that in the control group(all P＜0.05).After treatment,the serum PGE2 levels in both groups increased,while the PGF2α levels decreased.Moreover,the serum PGE2 level in the observation group was higher than that in the control group,and the PGF2α level was lower than that in the control group(all P＜0.05).After treatment,the plasma viscosity,whole blood viscosity and FIB levels of both groups decreased,and those of the observation group were lower than those of the control group(all P＜0.05).Conclusion:Guizhi Fuling Decoction retention enema combined with biofeedback electrical stimulation has a remarkable therapeutic effect on PCS.It can significantly alleviate patients'pain and varicose veins,increase venous blood flow velocity,and improve hemorheological indicators.