Exploration on the Differentiation and Treatment of Systemic Light Chain Amyloidosis Based on"Yin Marrow Toxins"
MA Guodong
CUI Siyuan
DU Shangyu
SI Yuping
WEI Wenjian
SHI Jingbo
LI Changnian
Abstract：In order to better understand systemic light chain amyloidosis(AL)from the perspective of traditional Chinese medicine,this disease is named"yin marrow toxins".It is believed that the key to the onset of this disease lies in"yin toxins",the pathological attribute of the accompanying symptoms is"yin",the lesion site is in the"marrow",and the forming pathological factors are"deficiency,blood stasis and phlegm",which generate toxic pathogenic factors that affect the organs,and the heart or kidney involvement is common.This disease often has a poor prognosis.Early diagnosis and treatment are of vital importance.Warming yang,tonifying deficiency,removing blood stasis and resolving phlegm can be used as the basic therapeutic principles to alleviate the manifestations of organ involvement.Clinically,syndromes such as spleen and kidney yang deficiency,heart and lung blood stasis,phlegm retention in the gastrointestinal tract,liver meridian stasis,qi deficiency obstruction,wind-dampness and skin accumulation,and sudden collapse of heart yang can be used as references to further explore the connection between traditional Chinese medicine and this disease.
Keywords：yin marrow toxinssystemic light chain amyloidosiswarming yang and tonifying deficiencyremoving blood stasis and resolving phlegm
Publication Date：2025-08-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：6( 869-874 )