Exploriation on Pathogenesis and Treatment Strategies of Premenstrual Dysphoric Disorder Based on the Theory of Liver Storing Blood
WANG Zijian
LI Shujing
WANG Haijun
XU Shuliang
GUO Yinghui
Abstract：Premenstrual dysphoric disorder(PMDD)is a common disease among women of childbearing age,characterized by periodic emotional abnormalities and physical symptoms,which seriously affects the quality of life of patients.This article discusses the pathogenesis and treatment strategies of PMDD based on the theory of"liver storing blood".The core pathogenesis of PMDD is that during the menstrual cycle,liver blood flows down to the Chong and Ren meridians in the uterus,resulting in temporary insufficiency of liver blood and subsequently causing abnormal circulation of liver qi.Insufficient liver blood leads to hyperactivity or stagnation of liver qi,manifested as abnormal emotions such as irritability,anger,depression and anxiety,accompanied by physical symptoms such as breast distension and pain and insomnia.By analyzing the dynamic changes of liver blood and liver qi in the three stages of premenstrual period,menstrual period and post-menstrual period,it is proposed that the periodic onset of PMDD is closely related to the imbalance of liver blood surplus and deficiency.In terms of treatment,it emphasizes"prevention before illness",advocating tonifying liver blood and harmonizing liver qi before menstruation,supplemented by strengthening the spleen and tonifying the kidneys to enhance blood production function,thereby alleviating the pathological state of liver failure to regulate the flow of qi.Clinically,prescriptions and medicinals that soothe the liver and regulate qi,nourish blood and soothe the liver[such as Xiaoyao Powder(逍遥散),Danggui Shaoyao Powder(当归芍药散),etc.]can be selected,and lifestyle adjustments can be combined to reduce the hidden consumption of liver blood.
Keywords：premenstrual dysphoric disorderpremenstrual syndromeliver storing bloodliver controlling disper-sionvisceral manifestion of the liver
Publication Date：2025-08-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：6( 853-857,874 )