JIANG Quan's Medication Regularity and Experience in Treatment of Scleroderma from the Liver

CHANG Tian; XIA Congmin; PENG Qiuwei; ZHANG Fuyuan; LI Yanting; JIAO Juan; JIANG Quan

doi:10.16295/j.cnki.0257-358x.2025.07.015

Abstract：Objective:To explore the prescription and medication regularities of Professor JIANG Quan in the treatment of scleroderma based on data mining and to explain her academic experience scientifically.Methods:The prescription data of Professor JIANG Quan in treating patients with scleroderma in the outpatient department in the past 10 years were collected.The high-frequency medication and the property,flavor and channel tropism were analyzed using Excel 2016.Association rules analysis,cluster analysis and factor analysis were conducted through IBM SPSS Modeler 18.0 and SPSS Statistics 26.0.Results:A total of 272 prescriptions were included,involving 231 traditional Chinese medicinals.The majority of the medicinals involved the liver,spleen,and lung meridians.The main functions were to tonify deficiency,promote blood circulation and remove blood stasis.The frequently used medicinals mainly included Danggui(Angelicae Sinensis Radix),Baishao(Paeoniae Radix Alba),Jixueteng(Spatholobi Caulis),Chuanxiong(Chuanxiong Rhizoma),Danshen(Salviae Miltiorrhizae Radix Et Rhizoma),Tongcao(Tetrapanacis Medulia),Chaihu(Bupleuri Radix),Fuling(Poria),Dilong(Pheretima).Cluster analysis yielded 7 combinations,and a total of 10 common factors were extracted.Conclusions:Based on inheriting the theory of"tonifying the spleen and stomach"of Professor LU Zhizheng,a master of traditional Chinese medicine,Professor JIANG attaches great importance to treating scleroderma from the liver.She believes that"deficiency of liver blood,stagnation of liver qi suppressing spleen qi and blocking lung qi"is the basic pathogenesis.In her prescriptions and medications,she advocates"nourishing blood and soothing the liver,strengthening the spleen and suppressing wood,and clearing the lungs and leveling wood".