Exploration on the Differentiation and Treatment of Multiple Organ Dysfunction Syndrome in the Elderly Based on the Theory of Latent Toxins
LIU Juan
XU Xiaowen
DAI Na
LI Zhengguang
Abstract：Multiple organ dysfunction syndrome in the elderly(MODSE)is a clinical critical syndrome with a complex pathogenesis and an extremely high mortality rate.The pathogenesis of this disease is complex.Generally,it is mainly characterized by deficiency in origin and excess in superficiality,with a mixture of deficiency and excess.By exploring the connection between the theory of latent toxins and MODSE,it is believed that the pathogenesis evolution law of MODSE is that in the early stage,there is deficiency of the body's healthy qi and excess of pathogenic factors,and the disease is latent.In the middle stage,phlegm and blood stasis interblock,lingering and consuming quietly.In the late stage,latent toxins are violent,stubborn,and changeable,which is the core pathogenesis that leads to the acute onset and aggravation of MODSE.Among them,the proportion of deficiency of body's healthy qi and excess of pathogenic factors in the early and middle stages is not much different and can be classified as the early stage of exhaustion.In the late stage,the main symptom is the deficiency of the body's healthy qi,and the latent toxins are violent and pathogenic,which can be classified as the exhaustion stage.In terms of treatment,staged treatment and differentiation is necessary based on the evolution pattern of latent toxins and the characteristics of the pathogenesis at different stages.In the early stage,it is advisable to warm yang,benefit qi,support the body's healthy qi,and consolidate the foundation.In the middle stage,it is advisable to eliminate dampness and phlegm,promote blood circulation and remove blood stasis.In the late stage,it is advisable to support the body's healthy qi while eliminating pathogenic factors to detoxify and eliminate toxins.Both the symptoms and the root cause should be taken into account in order to stop the disease progression as early as possible and prevent MODSE from transforming from"decline of all internal organs"to"exhaustion of all internal organs".
Keywords：multiple organ dysfunction syndrome in the elderly(MODSE)latent toxinssupporting the body's healthy qieliminating pathogenic factorsdetoxification
Publication Date：2025-06-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：6( 642-647 )