Discussion on Pathogenesis,Syndrome,and Treatment of Idiopathic Pulmonary Fibrosis Based on Unobstructed Flow of Yuanzhen in Five Zang-Organs
SUN Yuxiao
WANG Xiaodong
MA Xinlai
ZHANG Wei
Abstract：Idiopathic pulmonary fibrosis(IPF)belongs to the category of lung atrophy and lung impediment in traditional Chinese medicine.The pathogenesis of IPF is characterized by phlegm and blood stasis obstruction as the superficial manifestation and deficiency of qi and blood as the root cause,which is generally a condition of root deficiency and superficial excess.The Yuanzhen in five-zang organs are mainly composed of qi and blood,transformed by the congenital essence of the kidney,nourished by the acquired qi of water and grains from the spleen and the stomach,circulating through the triple energizer,and flowing throughout the zang-fu organs and meridians of the whole body,exerting functions such as nourishing and moistening,and defending against external pathogenic factors.The characteristics of the lung,which is responsible for dispersion and descent and is rich in qi and blood,are closely related to the unobstructed flow of the Yuanzhen in five-zang organs.Therefore,the treatment of IPF can be based on the unobstructed flow of the Yuanzhen in five-zang organs.In the early stage of IPF,the main pathological change is the disorder of qi movement,and there is no significant depletion or stagnation of the Yuanzhen in five-zang organs.The treatment should focus on eliminating pathogenic factors and protecting the defensive qi.In the middle stage,based on the disorder of qi movement,abnormal blood circulation mainly caused by blood stasis occurs.Although there is stagnation and deficiency of the Yuanzhen in five-zang organs,it is mainly limited to the lung.The treatment should combine both attacking and tonifying methods.In the late stage,due to the long-term disorder of qi and blood circulation,the Yuanzhen in five-zang organs is severely damaged and the flow of the Yuanzhen in five-zang organs is not smooth.The treatment should focus on nourishing and tonifying the Yuanzhen.
Keywords：idiopathic pulmonary fibrosisthe unobstructed flow of the Yuanzhenqi and bloodphlegm and blood stasis obstructionnourishing and tonifying the Yuanzhen
Publication Date：2025-05-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：6( 493-498 )