Professor YU Renhuan's Experience of Using Guizhi Gancao Longgu Muli Decoction(桂枝甘草龙骨牡蛎汤)in Treating Chronic Kidney Disease Complicated with Emotional Disorders
WANG Wenru
YANG Jiayi
ZHAN Jingyi
ZHAN Tian
YAN Lei
CHEN Yao
LIANG Ying
Abstract：Chronic kidney disease(CKD)is characterized by a poor prognosis and a long course.Moreover,patients with end-stage renal disease require expensive renal replacement therapy to sustain their lives.Therefore,most CKD patients endure heavy psycho-logical and economic burdens for a long time,and thus concurrently develop emotional disorders.Professor YU Renhuan proposed that the main pathogenesis of CKD complicated with emotional disorders is depression caused by kidney deficiency,including restlessness caused by deficiency of kidney yin resulting in fire without containment,fear caused by deficiency of kidney yang resulting in will without storage,and depression caused by deficiency of kidney qi resulting in qi without support,etc.Guizhi Gancao Longgu Muli Decoction(桂枝甘草龙骨牡蛎汤)has the efficacy of activating yang,restraining yang,and subduing yang to calm the mind.It can be used to treat restlessness caused by the disturbance of the mind and spirit by yang-pathogen due to kidney deficiency.Based on this formula,Professor YU treats CKD complicated with emotional disorders by adding prescriptions or drugs with efficacy of regulating the heart and calming the mind,warming yang and strengthening the spleen,and soothing the liver and relieving depression according to different syndrome types,which has achieved favorable therapeutic outcomes.One proved case is attached.
Keywords：chronic kidney diseaseemotional disordersGuizhi Gancao Longgu Muli Decoctionregulating the heart and calming the mindwarming yang and strengthening the spleensoothing the liver and relieving depressionYU Renhuan
Publication Date：2025-05-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：5( 489-492,509 )