Clinical Study on Poge Jiuxin Decoction(破格救心汤)in Treatment of Acute Heart Failure After Myocardial Infarction
CHEN Jingli
YUAN Kang
ZENG Yiyun
CHEN Guangmei
Abstract：Objective:To explore the clinical efficacy of Poge Jiuxin Decoction(破格救心汤)in the treatment of acute heart failure after myocardial infarction.Method:Ninety-one patients with acute heart failure after myocardial infarction were selected and divided by using random number table method,including 42 patients in the observation group and 49 patients in the control group.The control group was treated with conventional western medicine,and the observa-tion group was treated with Poge Jiuxin Decoction orally on the basis of the treatment of the control group.The changes of resting heart rate and systolic blood pressure before and after treatment were observed.N-terminal B-type natriuretic peptide(NT-proBNP),left ventricular ejection fraction(LVEF),left ventricular end-diastolic inner diameter(LVESD),6 min walking test(6MWT)and Minnesota Living with Heart Failure Questionnaire(MLHFQ)score were compared before and after treatment.The number of hospitalizations due to cardiovascular adverse events within half a year and the occurrence of cardiovascular adverse events during the study period in the two groups were analyzed.Results:There were no significant differences in resting heart rate,systolic blood pressure,LVEF and LVESD between the two groups before and after treatment(P＞0.05).Before treatment,there was no significant difference in NT-proBNP,6MWT and MLHFQ score between the two groups(P＞0.05).After treatment,NT-proBNP and MLHFQ score in both groups were lower than those before treatment,and 6MWT was higher than that before treatment,the difference was statistically significant(P＜0.05).After treatment,NT-proBNP in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of adverse cardiovascular events between the two groups and the number of hospitalizations due to cardio vascular adverse events within half a year(P＞0.05).Conclusion:Poge Jiuxin Decoction can improve short-term cardiac function of patients with acute heart failure after myocardial infarction,but it can not improve the long-term cardiac function.
Keywords：Poge Jiuxin Decoctionmyocardial infarctionacute heart failureheart functionevaluation of efficacy
Publication Date：2025-03-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：7( 308-314 )