Study on Regularities of Acupuncture and Moxibustion in Treatment of Prostate Cancer Based on Data Mining

WANG Shiheng; ZHANG Fengxia; ZHU Tingyu; QIN Peijie

doi:10.16295/j.cnki.0257-358x.2025.02.012

Abstract：Objective:To explore the rules of acupuncture and moxibustion prescription in the treatment of prostate cancer in the literature,in order to provide clinical references.Methods:Acupuncture prescriptions recorded in CNKI,Wanfang,VIP,Chinese Biomedical Literature Service System,Chinese Academy of Tradi-tional Chinese Medicine Folk Single Test Formula Database,SinoMed,PubMed,Web of Science,Embase and Cochrane Library were searched up from establishment of those database to July 1,2023.Data mining software was used to analyze the selection patterns of acupoints.Results:A total of 55 acupuncture prescriptions to treat prostate cancer were included,involving 56 acupoints.The high frequency acupoints include Guanyuan(CV4),Qihai(CV6),Shenshu(BL23),Tai-chong(LR3),Yinlingquan(SP9),and others.A total of 20 core acupoint combinations were obtained by association regularity analysis,with the most core combination was Qihai-Guanyuan.Conclusions:Through data mining of acupuncture and moxibustion points used in the treatment of prostate cancer in modern Chinese medicine,the matching regularities of acupoints were summarized.It was found that most of these points are located on the foot shaoyin kidney channel,foot jueyin liver channel,foot taiyang bladder channel,conception vessel,and foot taiyin spleen channel,indicating that prostate cancer is related to the kidney,bladder,liver,and spleen.The treatment primarily aims to tonify deficiencies,especially those of the spleen and kidney,aligning with the pathogenesis of original deficiency and insufficiency,and providing significant reference for the current treatment of prostate cancer.