Clinical Study on Treating Obesity in Adolescent Children of spleen deficiency and phlegm dampness with Modification of Fangji Huangqi Decoction(防己黄芪汤)Combined with Zhizhu Pill(枳术丸)
YANG Yuxin
WANG Mengran
ZHANG Heng
ZHANG Guiju
Abstract：Objective:To observe the clinical efficacy of Fangji Huangqi Decoction(防 己 黄 芪 汤)combined with Zhizhu Pill(枳术丸)in treating obesity in adolescent children of spleen deficiency and phlegm dampness type.Methods:Seventy cases of adolescents with simple obesity of spleen deficiency and phlegm dampness type were selected and randomly divided into a control group and a treatment group,with 35 cases in each group.The control group was given guidance to correct daily behavioral habits,while the treatment group received Fangji Huangqi Decoction combined with Zhizhu Pill with modifications,in addition to the correction of daily behavioral habits.Both groups were treated for 12 weeks.The clinical efficacy of the two groups was compared,along with changes in traditional Chinese medicine(TCM)syndrome scores,obesity indexes[body mass,body mass index(BMI)],and serum levels of high-density lipoprotein(HDL-C),low-density lipoprotein(LDL-C),triacylglycerol(TG),and total cholesterol(TC)before and after treatment.Results:The total effective rate of the treatment group was 85.71％,which was higher than that of the control group at 61.54％,and the difference was statistically significant(P＜0.05).After treatment,both groups showed a reduction in TCM syndrome scores,body mass,BMI,LDL-C,TG,and TC compared to before treatment.The differences of TCM syndrome scores and BMI between the groups were also statistically significant(P＜0.05).Conclusion:Fangji Huangqi Decoction combined with Zhizhu Pill can effectively treat obesity in adolescent children,reduce body mass and BMI.
Keywords：Fangji Huangqi DecoctionZhizhu Pilladolescent obesityspleen deficiency and phlegm dampnessbody mass index
Publication Date：2025-02-04
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：6( 178-183 )