Discussion on Mechanism of Depression Induced by Ulcerative Colitis from Perspective of"Spleen Storing Nutrient and Housing Idea"
LIU Wei
TIAN Fengliang
ZENG Jian
YUAN Ling
LIU Yu
QIU Hong
LU Qiongqiong
XU Jianzhong
Abstract："Spleen storing nutrient and housing idea"is initially recorded in Miraculous Pivot-Roots of Spirit,which reflects the function of spleen in transporting and transforming the essence of water and grains to the brain to nourish the"idea".If the function of the spleen is damaged,the function of"idea"will not be able to exert.The concept of this pathology is consistent with the pathological mechanism of ulcerative colitis-induced depression——the intestinal inflammatory response invades the central nervous system and other series of pathological reactions lead to damage to the brain hippocampus and ultimately induce depressive-like behavior.This paper elucidates the correlation between the traditional Chinese medicine theory of"spleen storing nutrient and housing idea"and the mechanism of depression induced by ulcerative colitis,with a prospect of applying the theory of"spleen storing nutrient and housing idea"in guiding the clinical diagnosis and treatment of depression induced by ulcerative colitis.
Keywords：ulcerative colitisdepressionspleen stor-ing nutrient and housing ideaclinical diagnosis and treatment
Publication Date：2024-08-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：5( 824-828 )