A Case Report of Clostridium Difficile Associated Diarrhea Treated with Modified Wumei Pill(乌梅丸)
ZHANG Yan
WANG Yunliang
Abstract:A case of Clostridium difficile associated diarrhea(CD AD)treated with modified Wumei Pill(乌梅丸)was reported.The patient had suffered from intermittent diarrhea for 3 years,which was aggravated by clostridium difficile infection for more than 3 months.The early standard treatment of western medicine did not achieve satisfactory effect.According to symptoms,and tongue and pulse diagnosis,patients were diagnosed as disharmony between liver and spleen,deficient cold in middle energizer according to traditional Chinese medicine(TCM)syndrome differentiation,and treated with oral administration of modified Wumei Pill to sooth liver,invigorate spleen,warm the middle,soften liver,astringe intestines and stop diarrhea.Two months after treatment,the glutamate dehydrogenase antigen and toxin test of Clostridium difficile were tested negatively,and symptoms like diarrhea,cold aversion in abdomen and scanty urine were also significantly relieved.Through the analysis of the diagnosis and treatment of this case and the review of relevant literature,the significance of Wumei Pill in the treatment of CDAD by the characteristics of soothing and softening the liver,warming the middle,combined application of cold and heat,and regulating vital energy were mastered,and then it should be promoted to treat various diarrhea-related diseases in clinic,which is also the essence of the treating different diseases with same method.
Keywords:Wumei PillClostridium difficileClostridium difficile associated diarrheatraditional Chinese medicine treatmentmedical case
Publication Date:2023-12-05
Online Publishing Date:2026-05-22(First online date of this platform, not the publication date of the document)
Pages:5( 1338-1341,1360 )
Shandong Journal of Traditional Chinese Medicine

Shandong Journal of Traditional Chinese Medicine

ISTIC
ISSN:0257-358X
Year, Vol.(Issue):2023,42(12)