Observation on Efficacy of Combination of"Ear Point-External Application-Enema"Based on"Sancai Theory"in Intervention of Mild to Moderate Acute Hyperlipidemic Pancreatitis

JU Wei; ZHOU Wenming

doi:10.16295/j.cnki.0257-358x.2023.12.011

Abstract：Objective:To analyze efficacy of the combination of"ear point-external application-enema"based on the"Sancai theory"on mild to moderate acute hyperlipidemic pancreatitis.Method:Totally,96 patients with mild to moderate acute hyperlipidemic pancreatitis were selected and randomly divided into three groups according to the number table method:enema group(group A),external application+enema group(group B),and external application+enema+ear point group(group C),32 patients in each group.Besides routine treatment,group A was further treated with enema by Chaishao Chengqi Decoction(柴芍承气汤);group B was further treated with external application of mirabilite bags based on the treatment in group A;group C was further treated with holographic scraping on the ear of midnight-noon ebb-flow and embedded pressing needle embedding in ear points based on the treatment in group B.Three sets of inflammatory indicators before and after treatment,serum tumor necrosis factor α(TNF-α),interleukin-6(IL-6),hypersensitive C-reactive protein(hs-CRP),gastrointestinal dynamics(recovery of exhaust,relief of abdominal distension,relief of abdominal pain,recovery of bowel sounds,and recovery of defecation),intestinal mucosal function(endotoxin,diamine oxidase),immune function(CD3+,CD4+,CD8+),clinical related indicators[Ranson score,acute physiology and chronic health evaluation(PACHE)Ⅱ score,triglyceride(TG)level].Results:As to inflammatory markers,group C was lower than other two groups on levels of TNF-α and Hs-CRP(P＜0.05),and was lower than group A(P＜0.05)with no difference compared to group B(P＞0.05)on IL-6.There was no statistically significant difference in the recovery time of gastrointestinal function and the relief time of abdominal distension among the three groups(P＞0.05).The recovery time of bloating,defecation,and pain relief in group C were significantly shorter than those in other two groups(P＜0.05).The recovery time of intestinal sounds in group C was significantly lower than that in group A(P＜0.05),with no difference compared to group B(P＞0.05).The intestinal mucosal function test showed that the levels of endotoxin and diamine oxidase in group C were lower than those in the other two groups(P＜0.05).On immune function,levels of CD3+and CD4+in group C were higher than those in other two groups(P＜0.05),and there was no statistically significant difference in CD8+indicators among the three groups(P＞0.05).On clinical related indicators,the Ranson score and PACHE Ⅱ score in group C were lower than other two groups,with statistical differences(P＜0.05).The TG level in group C was lower than that in group A(P＜0.05),with no difference compared to that in group B(P＞0.05).Conclusions:The combined regimen of"ear point-external application-enema"based on"Sancai Theory"can reduce the expression of inflammatory factors,improve gastrointestinal function,and enhance immunity in the treatment of mild to moderate acute hyperlipidemic pancreatitis,with significant efficacy.