Clinical Study on Shengjing No.3 Formula(生精3号方)in Treating Oligoasthenozoospermia Infertility of Kidney Deficiency and Blood Stasis Type
LIANG Shijia
MAO Jianmin
HAN Wenjun
LIU Peng
YU Quanyao
WANG Junbo
LIANG Bowen
SUN Jianming
Abstract：Objective:To observe the clinical effect of Shengjing No.3 Formula(生精3号方)in treating oligoasthenozoospermia infertility of kidney deficiency and blood stasis type.Methods:A total of 120 patients with oligoasthenozoospermia infertility of kidney deficiency and blood stasis type were divided into the observation group and the control group according to random number table method,with 60 cases in each group.The observation group was treated with Shengjing No.3 Formula,and the control group was treated with Wuzi Yanzong Pill(五子衍宗丸).Both groups were treated for 3 months.After 3 months of treatment,the sperm density,percentage of sperm progressive motility rate(PR),normal sperm form rate,sperm DNA fragment index(DFI),semen berry sugar,a-glucosidase,seminal plasma zinc and traditional Chinese medicine(TCM)syndrome score of the two groups were compared to evaluate the clinical efficacy and safety.Results:After treatment,the sperm density,PR,normal form sperm rate,TCM syndrome score,DFI and semen berry sugar level in the observation group were improved compared with those before treatment(P＜0.05),while the sperm density,PR,normal form sperm rate and TCM syndrome score in the control group were improved compared with those before treatment(P＜0.05).The improvement of sperm density,PR,normal sperm rate,TCM syndrome score and DFI in the observation group were better than those in the control group(P＜0.05).After treatment,13 cases were cured in the observation group,the total effective rate was 83.3％,and 8 cases were cured in the control group,the total effective rate was 68.3％.The curative effect of the observation group was better than that of the control group(P＜0.05).No adverse reactions occurred in both groups.Conclusion:Shengjing No.3 Formula can safely and effectively improve the sperm density,PR and normal form sperm rate of oligoasthenozoospermia infertility patients of kidney deficiency and blood stasis type,so as to increase the pregnancy ratio of spouses.
Keywords：Shengjing No.3 FormulaWuzi Yanzong Pilloligoasthenozoospermiamasculine sterilitykidney deficiency and blood stasis
Publication Date：2023-10-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：5( 1062-1066 )