Establishment and Practice of Pathogenesis Theory of Hypertensive Yang-qi Hyperactivity and Reverse
ZHANG Lei
JIANG Feng
LI Yunlun
Abstract：Systematically summarizes the understanding of hypertension in traditional Chinese medicine,endoses liver-yang hyperactivity with new connotation,and constructs a new pathogenesis theory of Yang-qi hyperactivity and reverse in hypertension.It is suggested that Yang-qi hyperactivity and reverse is a key pathogenesis in the pathological mechanism of hypertension,which runs through the whole process of the occurrence,development and syndrome evolution of hypertension.In the early stage of hypertension,most of the symptoms are liver-yang excess and pure solid syndrome without deficiency,for the syndrome of liver-yang hyperactivity.After a long time,the yin of the liver and kidney is damaged,causing yin deficiency and yang hyperactivity,then it develops to the middle stage,and the deficiency and excess are mixed,which is the syndrome of yin deficiency and yang hyperactivity.If the disease is not cured for a long time,yin deficiency damages yang and the disease develops to the later stage and leads to the formation of yin and yang deficiency(partial yin deficiency)syndrome.Yang-qi hyperactivity and reverse runs through the above three stages,but the mechanism of Yang-qi hyperactivity and reverse is different in different stages,and can be treated according to the pathogenesis evolution of different stages.And revealed the biological basis of the syndrome group of hypertension Yang-qi hyperactivity from the aspects of renin angiotensin aldosterone system(RAAS)activation,vascular endothelial dysfunction,insulin resistance and so on.
Keywords：hypertensionYang-qi hyperactivity and reversepathogenesis theoryTengyi Jiangya Formula(藤菔降压方)Gouteng Xuanshen Formula(钩藤玄参方)Yishen Jiangya Formula(益肾降压方)
Publication Date：2023-09-05
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：8( 905-912 )