Clinical Study of Gastroesophageal Reflux Cough of Damp Heat Type Treated with Shangjiao Xuanbi Decoction Combined with Esomeprazole
LI Junmin
LI Yan
SHI Zhimin
Abstract：Objective: To observe the clinical effect of Shangjiao Xuanbi Decoction combined esomeprazole in the treatment of gastroesophageal reflux cough (GERC) of damp heat type. Methods: One hundred patients with GERC were randomly divided into two groups, 50 cases in each group. The control group was given oral administration of esomeprazole magnesium enteric-coated tablets and the treatment group was given Shangjiao Xuanbi Decoction besides the medicine of the control group. After 8 weeks of treatment, changes of the cough score and traditional Chinese medicine (TCM) symptom score in the two groups were recorded to evaluate the clinical efficacy. Results: After the treatment, the TCM symptoms (heartburn, acid regurgitation, chest pain, upper abdominal pain, throat discomfort) and cough symptom scores of the treatment group were lower than those of the control group, with statistical significance (P< 0.05). In the treatment group and the control group the total effective rate was 94％ and 78％, respectively, with statistical significance (P< 0.05). Conclusion: Shangjiao Xuanbi Decoction combined with esomeprazole can significantly relieve TCM symptoms and cough in patients with GERC and cough symptoms, with obviously improved clinical efficacy.
Keywords：gastroesophageal reflux coughdamp heat typeShangjiao Xuanbi Decoctionesomeprazole
Publication Date：2018-01-01
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：3( 472-474 )