Determination Content of α-asarone,β-asarone and asarone in Huannao Yicong Formula by HPLC
Liang Xiaodong
ZHANG Xi
WEI Yun
LIU Longtao
LI Hao
Abstract：Objective:To determine the content of α-asarone,β-asarone and asarone in Huannao Yicong for-mula by HPLC. Methods:The chromatographic separations were performed on an Agilent Eclipse XDB-C18 column(250 mm×4.6 mm i.d.,5μm) with 30℃. The mobile phase consisted of methanol and 0.1％ formic acid water. The wavelength of detector was set at 265 nm,the flow rate was 1.0 mL/min. The content ofα-asarone,β-asarone and asarone was detected respectively. Results:The content of α-asarone in Rhizoma A-cori Tatarinowii and HNYCF was 1.2742 and 3.4891 mg/g,the content of β-asarone was 7.6301 and 35.836 mg/g,the content of asarone was 0.8337 and 7.8083 mg/g. Conclusion:The contents of α-asarone,β-asarone and asarone in HNYCF were 2.7,4.7 and 9.7 times than in Rhizoma Acori Tatarinowii,which indicated that the dissolution rate of the three could be increased after compatibility.
Keywords：HPLCHuannao Yicong formulaα-asaroneβ-asaroneasaronedetermination of content
Publication Date：2018-01-01
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：4( 67-70 )