Observation of Efficacy of Modified Banxia Baizhu Tianma Decoction on Treating Acute Ischemic Stroke

MA Jie

Abstract：Objective:To observe the efficacy of Jiawei Banxia Baizhu Tianma decoction on treating patients with acute ischemic stroke. Methods:A total of 140 patients with acute ischemic stroke of wind and phlegm blockage channel syndrome were randomly divided into the observation group and the control group ,with 70 cases in each group. The control group was given conventional western medicine treatment ,and the observa-tion group was given Jiawei Banxia Baizhu Tianma decoction besides the treatment in the control group. Af-ter 2 weeks,the clinical efficacy and changes of serum inflammatory factors (IL-6,hs-CRP,TNF-α) and coag-ulation function(PT,TT,APTT,FIB) of the two groups were observed. Results:①Comparison of clinical effi-cacy:in the observation group and the control group ,the general cure rates were 42.86% and 27.14%,the significant improvement rates were 38.51% and 32.86%,the improvement rates were 14.29% and 24.29%,re-spectively. The difference was statistically significant (P<0.05);②Comparison of inflammatory factors levels:There was significant difference on levels of IL-6,hs-CRP,TNF-α in these two groups(P<0.05),all of them decreased gradually with time increasing(P<0.05),and the decrease in the observation group was greater than that in the control group (P<0.05);③Comparison of coagulation function levels:There was significant difference of PT,APTT,TT,FIB in the two groups(P<0.05),PT,APTT and TT increased with time increasing (P<0.05),while FIB decreased(P<0.05);the change in the observation group was greater than that in the control group(P<0.05). Conclusion:Jiawei Banxia Baizhu Tianma decoction can effectively improve the clini-cal efficacy on acute ischemic stroke ,and its mechanism may be related to inhibiting inflamma-tory reaction and improving coagulation function.