A Study of the Extraction Technology for Xiawang Sanjie Capsule
WEI Ran
XU Li
LIN Guitao
Abstract：Objective:To determine the extraction technology of the Xiawang Sanjie capsule,and to ensure its safety and effectiveness. Methods:According to the properties of the active ingredients of each Chinese herb, herbs were extracted using decoction method and ethanol reflux extraction. The optimized extraction condi-tions were determined by orthogonal test,with the extracted amount,the amount of ethanol soluble matter and the amount of the n-butanol soluble matter as the index. Results:Xiakucao(Prunella),Wang Bu Liu Xing (Vaccaria),Zhe Bei Mu (Fritillaria),Shan Cigu (indica),and Chaihu (bupleurum) were extracted with 70%ethanol reflux extraction for 2 time 3 hr per for each time,with 10 folds and 8 folds amount of solvent added,respectively. After extracted for volatile oil,Ezhu (Curcuma),Baizhu (Atractylodes),Xiangfu (Cyperus) were mixed with mu li(Concha Ostreae),Kunbu(Thallus Laminariae) and water for 1 hr,and then decocted for 2 times,2 hr per time,with 8 folds and 6 folds amount of water,respectively. Conclusion:The extraction technology could extract the active ingredients effectively,which can ensure the effectiveness and safety of the preparation.
Keywords：Xiawang Sanjie capsulehyperplasia of mammary glandsextraction technologyorthogonal test
Publication Date：2017-01-01
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：4( 237-240 )