Meta-analysis of Huoxue Jiedu Medicine Combined with Chemotherapy Treating Ad-vanced Gastric Cancer
WANG Xiaoyan
CAO Zhiqun
Abstract：Objective:To evaluate the effectiveness and safety of Huoxue Jiedu medicine combined with chemotherapy in the treatment of advanced gastric cancer. Methods:Using the evaluation method of Cochrane system,we have searched VIP,CNKI,CBM,WanFang database,collected randomized controlled trials about Huoxue Jiedu medicine combined with chemotherapy in the treatment of advanced gastric cancer. According to the inclusion and exclusion criteria,quality assessment,screening and extracting the effective data,Meta-! analysis was performed with RevMan 5.0 software. Results:In 14 articles,901 patients met the inclusion cri-teria and enter the study. The results of Meta-analysis showed,improving the clinical efficacy,clinical symp-tom and life quality,reduce the reaction of digestive tract,blood cell toxicity and liver and kidney toxicity, Huoxue Jiedu medicine combined with chemotherapy was better than alone western medicine chemotherapy for advanced gastric cancer , with significant difference ( P<0 . 01 ) . Conclusions:Huoxue Jiedu medicine has certain auxiliary therapeutic effect on patients with advanced gastric cancer. It could improve the clinical ef-ficacy,clinical symptom and life quality,reduce the reaction of digestive tract,blood cell toxicity and toxicity of liver and kidney.
Keywords：Huoxue Jiedu medicineadvanced gastric cancerrandomized controlled trialsMeta-analysis
Publication Date：2015-01-01
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：6( 736-741 )