Clinical Study of Primary Sjogren’s Syndrome Treated by Nourishing Liver and Kidney

MO Xiaoying

Abstract：Objectives:To observe the clinical efficiency of primary Sjogren’s syndrome (pSS) patients treated by nourishing the liver and kidney. Methods:Totally 40 postmenopausal female pSS patients with syndrome of Yin deficiencies of the liver and kidney were randomly divided into two groups ,the treatment group and the control group 20 cases in each group. The control group was administered hydroxychloroquine (HCQ) sulfate tablet. In addition,the treatment group was prescribed Chinese medicine of nourishing the liver and kidney. Three-month treatment was as one course. After one treatment course,the clinical efficiency,the changes in symptom scores,tear quantity,salivation quantity,immuno-infective indices were observed to com-pare between both groups. Results:The total effective rate of the treatment group (85%) was significantly higher than that(55%) of the control group(P<0.05).The scores of clinical symptoms,tear quantity and sali-vation quantity of both groups were significantly improved(P<0.01),while the improvement in the treating group was more obvious than that in the control group(P<0.01). In both groups,immunoglobulin G(IgG), immunoglobulin A(IgA),immunoglobulin M(IgM),erythrocyte sedimentation rate(ESR) and the C reactive protein(CRP),were significantly improved than those before treatment(P<0.05),but no significant difrerences were found of two groups after treatment ( P>0 . 05 ) . Conclusion:The combination of Chinese medicine of nourishing the liver and kidney and HCQ is more effective on pSS than single use of HCQ.