Reseach on Screening of Effective Antiviral Parts of Mentha Haplocalyx
CHEN Fei
YAO Meiyue
ZHANG Xia
ZHOU Changzheng
Abstract：Objective:To determine the effective anti-herpes simplex virus(HSV) part of mentha haplocalyx by anti-HSV research in vitro on 12 chemical parts of mentha haplocalyx extracted by macroporous resin ad-sorption. Methods:The water decoction of mentha haplocalyx was concentrated to certain volume and the samples was put on the macropore adsorption resin. The samples was washed by water,25% ethanol,50%ethanol and 75% ethanol. The in vitro effect of anti HSV-1 was evaluated by in vitro infection model of HSV-1-Hep 2 cells. The cytopathic effect(CPE) was observed by microscope,the neutral red staining A540 value was determined by ELIASA and the therapeutic index(TI)was calculated. Results:The NO.2 water elu-tion has remarkable anti HSV-1 effect and the TI was 74.3. Conclusion:The water soluble ingredients of mentha haplocalyx has remarkable intibitory effect on HSV-1.
Keywords：mentha haplocalyxeffective partmacroporous resinherpes simplex virusantivirus
Publication Date：2015-01-01
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：3( 289-291 )