Study of the Anti-Temulence Effect of Liver-protective Oral Solution for Temulence Mice
ZHENG Lifa
DENG Jin
ZHANG Zhenhai
LYU Huixia
Abstract：Objective:To investigate the anti-temulence effects and mechanism of the liver-protective oral solu-tion ( LPOS ) on temulence mice . Methods:Alcoholism mice model were established by single gavage using Erguotou(56%,Chinese white liquor) 15 mL/kg. Then high,moderate and low dosages of LPOS were given to above formed intoxicated mice to investigate its anti-temulence effect,using the duration time of righting re flex(endurance time to alcohol),the disappear time of righting reflex(anti temulence time) and intoxicated rate as index. Results:Compared with control group,the duration time of righting reflex in treatment groups was significantly prolong(P<0.01),while its disappear time of righting reflex and mice’s intoxicated rate were significantly decreased(P<0.05 or P<0.01). Conclusion:The LPOS has the function of anti temulence for intoxicated mice.
Keywords：liver-protective oral solutiontemulence modelanti-temulence effectmouse
Publication Date：2014-01-01
Online Publishing Date：2026-05-22(First online date of this platform, not the publication date of the document)
Pages：3( 478-480 )