Research progress on antiarrhythmic effects and mechanisms of SGLT2 inhibitors
ZHONG Peng
ZHANG Chenghu
CAO Xiancun
Abstract：Sodium-glucose cotransporter 2 inhibitors(SGLT2i)are a novel oral hypoglycemic agents with good cardio-vascular protective effect.Multiple studies have evidenced that SGLT2i can significantly reduce the risk of heart failure,car-diovascular death,and delay the progression of chronic kidney disease.Recent studies have found that SGLT2i can reduce the occurrence and progression of arrhythmia.However,the role of SGLT-2i against arrhythmias and its exact mechanism are not fully elucidated.This paper aimed to summarize the existing evidence from basic studies and clinical reports,in order to further explore the anti-arrhythmic mechanism of SGLT2i and provide a new direction for the prevention and treatment of arrhythmias.
Keywords：Sodium-glucose cotransporter 2InhibitorArrhythmia
Publication Date：2025-10-30
Online Publishing Date：2025-11-26(First online date of this platform, not the publication date of the document)
Pages：8( 1012-1019 )