Research progress of masitinib,an antitumor drug in the treatment of neurodegenerative diseases
SHEN Qianhui
JIA Kang
LIU Yuan
ZHANG Zhixian
MAI Chengxiong
PI Rongbiao
ZHOU Sigui
Abstract:The prevalence of neurodegenerative diseases such as Alzheimer's disease(AD),amyotrophic lateral sclero-sis(ALS),and multiple sclerosis(MS)is increasing annually,yet effective therapeutic drugs remain elusive.Masitinib,o-riginally developed as a tyrosine kinase inhibitor for cancer treatment,has recently shown potential neuroprotective effects in various neurological disorders.This review summarized the research progress of Masitinib in the treatment of AD,ALS and MS.
Keywords:MasitinibAlzheimer's diseaseAmyotrophic lateral sclerosisMultiple sclerosis
Publication Date:2025-03-30
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:8( 257-264 )
