Research advances on cellular membrane nanovesicles for tumor vaccines
ZHAO Jianing
MA Tingting
KUANG Xiaoqin
HAO Mingyu
LI Chunjiayu
TU Jiasheng
SUN Chunmeng
WU Yanping
CHEN Qian
Abstract：In recent years,breakthroughs have been made in tumor immunotherapy.Tumor vaccines can overcome immunosuppression by enhancing immunogenicity,thereby activating immunity to recognize and kill tumor cells,which is a promising immunotherapy modality.Biomimetic cellular membrane nanovesicles with the advantages of tumor specific targeting,prolonged half-life and immune activation effects have potential to flourish the design of tumor vaccines.In this review,we summarized the recent progresses of various cellular membrane nanovesicles in the application of tumor vaccines,discussed their characteristics,preparation,characterization and modification methods,and analyzed the challenges in clinical application.
Keywords：Tumor immunotherapyTumor vaccinesCellular membrane nanovesiclesDrug delivery system
Publication Date：2025-02-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：10( 155-164 )