Research progress on anti-tumor effects of coumarin and its derivatives
ZHANG Lu
ZHANG Wen
ZOU Liyi
YIN Ting
LIU Yi
Abstract：Coumarins and their derivatives belong to a class of compounds with the core structure of benzo-α-pyrone.They have garnered significant interest from researchers due to their potent antitumor activity.This paper presents a compre-hensive review of the recent research literature on coumarins and their derivatives in the context of antitumor activity,en-compassing their respective mechanisms of action.The objective is to establish a scientific foundation for advancing the re-search and development of coumarin and its derivatives,as well as to advocate for their utilization in cancer therapy.
Keywords：CoumarinCoumarin derivativesAntitumor activityMechanism
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 1212-1219 )