Research progress on rotavirus and rotavirus vaccines
LIU Jiwei
WANG Weijian
WU Zhiang
SHI Feng
XIAN Ruiqing
LIANG Haiyan
Abstract：Rotavirus is an enteric virus that can cause intestinal infections leading to diarrhea and vomiting.Due to the immature immune systems of infants and young children,they are more susceptible to rotavirus infection,which is a leading cause of diarrhea-related hospitalizations among infants and young children.Rotavirus is highly contagious and spreads pri-marily through the fecal-oral route,with outbreaks typically occurring in autumn and winter.Currently,there is no specific antiviral drug for rotavirus,making rotavirus vaccination the most effective measure for preventing acute gastroenteritis caused by this virus.This article provides a review of the biological characteristics,epidemiological features,clinical manifes-tations,and the development and application of rotavirus vaccines.
Keywords：RotavirusEpidemiologyVaccine development
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1125-1130 )