Effcet of different sterilization processes on the quality of Carthami Flos raw powder evaluated by AHP-entropy weight TOPSIS mixed weighting method
ZHU Wenchao
CUI Linlin
GUAN Yongxia
ZHANG Guimin
Abstract：Objective A hybrid AHP-entropy weight TOPSIS weighted method was used to investigate and optimize the optimal sterilization process for the raw powder of Carthami Flos.Methods The content and sterilization rate of two components,hydroxy safflower yellow A and kaempferol,were used as evaluation indicators.The weight coefficients of each indicator were determined using the AHP-entropy weight TOPSIS mixed weighting method.Comparison of the effects of four sterilization processes,namely dry heat sterilization,wet heat sterilization,ultraviolet sterilization,and irradiation sterilization,on the quality of safflower powder before and after sterilization were compared.Results The AHP-entropy weight TOPSIS comprehensive evaluation results indicate that the order of the four sterilization processes affecting the quality of safflower raw powder is irradiation sterilization,ultraviolet sterilization,dry heat sterilization,and wet heat steriliza-tion.Compared with the original powder before sterilization,there was no significant change in the content of hydroxy safflow-er yellow A and kaempferol in the irradiated sterilization at a dose of 9 kGy or above,and the sterilization rate was 98.79％;Under humid heat sterilization conditions,the quality of safflower raw powder significantly decreased,and hydroxy safflower yellow A was not detected after sterilization.Conclusion Compared with other sterilization processes,irradiation sterilization is more suitable for safflower raw powder,and the irradiation dose is determined to be 9 kGy,which can ensure the sterilization effect while retaining its effective ingredients to the greatest extent.The optimal sterilization process has good repeatability,stability,feasibility,safety and efficiency,and can be used for industrial large-scale production.
Keywords：Carthami FlosAHP-entropy weight TOPSIS mixed weighting methodSterilization processIrradiation sterilizationHydroxy safflower yellow AKaempferolQuality evaluation
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 962-967 )