Rapid identification of the chemical constituents in the fructus of Polygounum orientale by UPLC-Q-Orbitrap-MS
BIAN Xing
XIA Linbo
DENG Shiren
SUN Lu
YANG Hao
Abstract：Objective To establish a rapid identification method for the chemical components in the fructus of Poly-gounum orientale.Methods The MS1 and MS2 spectral data collected in both positive and negative ion modes was acquired with UPLC-Q-Orbitrap-MS.The constituents were identified by deducing the fragmentation patterns and comparing with mass databases(MassBank,mzCloud),literature data,and reference materials.Results A total of 54 chem-ical components were identified from the fructus of P.orientale,mainly including flavonoids,phenolic acids,alkaloids,etc.A-mong them,15 components were first discovered from the fructus of P.orientale and also from the whole plant of P.orientale.Conclusion This study can provide a basis for in-depth quality evaluation and pharmacological substance basis research for the fructus of P.orientale.
Keywords：Fructus of P.orientaleChemical constituentsUPLC-Q-Orbitrap-MSMass fragmentation patterns
Publication Date：2024-03-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：7( 243-248,287 )