Study on the antidepressant effect of Yuanbaocao
YANG Daixiao
LIANG Yuheng
HE Chiming
TAN Lirong
LIANG Xuxia
ZHANG Lei
Abstract：Objective A preliminary study was conducted on the antidepressant effect of Yuanbaocao,a traditional Chinese medicine.Methods The rats were randomly divided into groups.Except for the blank control group,the other groups were subjected to chronic unpredictable stimulation experiments for modeling.The high,medium,and low dose groups of Yuanbaocao were administered by gavage,and the model group and the blank control group were administered the same volume of physiological saline by gavage.At the same time,a weekly behavioral despair experiment in rats(including forced swimming experiment and tail suspension experiment)was conducted to evaluate the antidepressant effect of Yuanbaocao.Results The results showed that the medium and high dose Yuanbaocao groups could better reverse the despair behavior and emotional state of depressed rats.Conclusion Yuanbaocao has a good antidepressant effect.
Keywords：YuanbaocaoAntidepressantBehavioral experiment
Publication Date：2023-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 978-981 )