Research progress on tumor thermo-chemotherapy based on nano-hyperthermia agents
GUO Hui
XU Yue
Abstract：As hyperthermia can enhance cytotoxicity of chemotherapeutic drug significantly,the thermo-chemotherapy,combining hyperthermia and chemotherapy,could achieve desired curative effect at lower drug dose.However,the efficiency of thermo-chemotherapy is determined completely by targeting hyperthermia in tumor tissue,which is limited by traditional whole-body heating.To overcome the shortage of traditional whole-body hyperthermia,some nano hyperthermia agents,converting infrared light or magnetic energy into thermal energy efficiently,have become promising candidates on targeting hyperthermia of tumor.Especially nano hyperthermia agents can be encapsulated with chemotherapeutic drugs simultaneously to form co-delivery,which could improve the synergetic efficiency of hyperthermia and chemotherapy.Therefore,thermo-chemotherapy based on nano-hyperthermia agents has been certificated as a promising cancer treatment.
Keywords：Tumor chemotherapyHyperthermiaNano-hyperthermia agentsThermo-chemotherapy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 353-355,359 )