The effect of pyroptotic in gouty arthritis regulated by NLRP3 and TLR4
LU Guo
ZHENG Dongsen
LI Hanwen
HONG Hao
Abstract：Pyroptotic is a strongly pro-inflammatory process of programmed cell death mediated by caspase-1.Pyroptotic,regulated by NLRP3 inflammasome and TLR4 signaling pathways together,plays an important role in the process of gout arthritis disease.This paper systematically reviewed about pyroptotic mechanism system in gouty arthritis,provided direction for the research on new drugs.
Keywords：PyroptoticGouty arthritisNLRP3Caspase-1TLR4
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 292-294,304 )