Research progress and mechanism of anti-tumor peptides drugs
WANG Shujing
LIU Huan
ZHAO Jiankai
REN Shuang
SUN Weiwei
ZHANG Wenjun
ZHANG Jianing
ZHANG Han
Abstract：Cancer is a kind of malignant disease which is a difficult problem in the world.At present,many clinical therapy and drugs are unable to avoid the drawbacks such as poor targeting,strong side effects and drug resistance.It is im-portant to look for anti-tumor drugs which are high effective,low toxic and easily available.Peptides stand out because of their features in many kinds of anti-tumor drugs,that depends on their small molecular weight,strong targeting,high activi-ty,low toxicity,easy to wear membrane and so on.Peptides have get extensive attention in the anti-tumor experimental study and clinical application.This paper classified anti-tumor peptides according to the mechanism and sources,respectively in-troduced apoptosis-promoting peptides,immunotherapied peptides,fusional peptides and other peptides,in the hope of pro-viding reference for screening,classifying and studying anti-tumor peptide.
Keywords：Anti-tumorCell apoptosisFusion peptidesImmunotherapy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 717-720 )