Research progress on the mechanism and IR time in MCAO/IR model rats with string-fastenting method
CHEN Dandan
XIE Xiaofang
AO Hui
PENG Cheng
Abstract:The MCAO/IR model in rats induced by thread embolism in middle cerebral artery is the most common used animal model in the research of ischemic brain injury.In recent years,many researches has been conducted on this animal model.This article reviewed the correlation in the time of ischemia-reperfusion( IR)and the mechanism,aimed to provide references for the selection in IR time and evaluation index in drug research and also provide some clues for the future study in MCAO/IR model rats.
Keywords:String-fastenting methodMCAOTime of IRMechanism
Publication Date:2016-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 538-541 )
Journal of Pharmaceutical Research

Journal of Pharmaceutical Research

ISSN:2095-5375
Year, Vol.(Issue):2016,35(9)