Preparation of Sodium Faropenem Orally Disintegrating Tablets by freeze - dried methods
ZHU Yaoliang
CHEN Xiaowei
HAO Guizhou
Abstract:Objective To optimize the formulation of Sodium Faropenem Orally Disintegrating Tablets and detect the dissolution in vitro. Methods Sodium Faropenem Orally Disintegrating Tablets was prepared by freeze - dried methods, and the formulation was optimized with the disintegrating time,friability and dissolution rate as parameters by orthogonal de-sign. Results The tablets prepared by optimum formulation were well - tasted,disintegrating fast,and had low friability. The dissolution was up to 95% within 3 min in vitro. Conclusion Sodium Faropenem Orally Disintegrating Tablets can be prepared successfully using the formulation in this research.
Keywords:Sodium faropenemOrally disintegrating tabletsFreeze - dried methods
Publication Date:2016-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 401-403 )
