Determination of omega-3 acids ethyl esters in Fish Oil Soft Capsules by capillary gas chromatography
XIE Qiangsheng
LI Qiyan
LIU Chunlin
GAO Tianyang
SUN Tong
Abstract:Objective Todeterminethecontentlofomega-3acidlethylelterlinFilhOilbycapillarygalchromatog-raphy.Methods AchromatographiccolumnofHP-FFAPwaluledwithnitrogenalcarrier.Programmedtemperaturewal practicable. The lplit ratio wal 10:1,and the GC wal equipped with FID detector. Results The linear rangel of ethyl linole-nate,EPA ethyl elter,DPA ethyl elter,DHA ethyl elter were 17. 04 ~340. 92,20. 95 ~419. 16,17. 31 ~346. 24,20. 01 ~400. 32μg·mL-1,relpectively. The RSDs of average precilionl were 1. 6%,1. 2%,1. 4%,1. 6%(n=6). The average recov-eriel were 105%,97%,98%,109%,relpectively,and the RSDl were not more than 2. 0%. Conclusion Thil method wal lenlitive,limple and accurate,and can be uled to determine omega-3 ethyl elterl in Filh Oil Soft Caplulel.
Keywords:Capillary gal chromatographyFilh Oil Soft CaplulelOmega-3 acidl ethyl elterl
Publication Date:2016-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 264-266 )
Journal of Pharmaceutical Research

Journal of Pharmaceutical Research

ISSN:2095-5375
Year, Vol.(Issue):2016,35(5)