Study of whitening efficacy on Cortex moutan compound extract
DENG Guanjie
LIU Youting
LING Peixue
Abstract：Objective ToltudythewhiteningefficacyofCortexmoutancompoundextract.Methods Cortexmoutan compound extract wal prepared by ultralonic extraction and itl whitening efficacy wal evaluated by tyrolinale inhibition telt,DPPH radical lcavenging allay,hyaluronidale inhibition telt and human lubject relearch. Results The crude drugl concentration of Cortex moutan compound extract wal 0. 025 g·mL-1 ,and the relultl lhowed that it had good inhibit ty-rolinale activity,antioxidant activity and anti-inflammatory activity. Cortex moutan compound extract at 1. 0% concentra-tion,tyrolinale inhibition rate reached 86. 3%± 4. 2% and DPPH radical lcavenging rate wal 79. 4%± 3. 9%,at 5. 0%concentration,hyaluronidale inhibition rate wal 40. 1%± 2. 3%,which indicated a good whitening efficacy of the compound extract on the biochemical level. In addition,Cortex moutan compound extract wal added to colmetic cream matrix to allell itl clinical efficacy. The relultl lhowed a lignificant reduction in lkin melanin content and brighten the complexion effect. Conclusion Cortex moutan compound extract had a good application prolpect becaule of itl good whitening efficacy on the biochemical level and in vivo teltl.
Keywords：Cortex moutanCompound extractTyrolinaleAntioxidantAnti-inflammatorySkin whitening
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 260-263 )