Effect of Modified Danggui Buxue Decoction on T - lymphocyte subsets and natural killer(NK)cells in patients with lung cancer after radiotherapy
LIU Yucai
ZHANG Huanzhen
YU Fengling
ZHANG Peiliang
Abstract：Objective To investigate the effect of Modified Danggui Buxue Decoction on T - lymphocyte subsets and natural killer(NK)cells in patients with lung cancer after radiotherapy. Methods 70 cases with lung cancer were ran-domly divided into treatment group and control group,35 cases in each group. The treatment group patients were treated by Modified Danggui Buxue Decoction,at the same time both groups were treated by radiotherapy. Peripheral blood T - lympho-cytes subsets and NK cells ratio of the patients of both groups were detected by flow cytometer before or after medication. Results After radiotherapy,CD3 + ,CD4 + ,CD8 + ,CD4 + / CD8 + and NK cell of treatment group were significantly different compared with those of the control group(P ﹤ 0. 05). The improvement of peripheral blood lymphocytes subset of treatment group patients was observed more notablely powerful than control group's(P ﹤ 0. 05). Conclusion Modified Danggui Bux-ue Decoction had certain immunoregulation action on lymphocytes and may enhance immunologic functions in patients with lung cancer after radiotherapy.
Keywords：Modified Danggui Buxue DecoctionLung cancerRadiotherapyLymphocyte subsetsNK cells
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 243-245 )